Colesevelam Hydrochloride + Olmesartan Medoxomil Hydrochlorothiazide Interaction

Moderateinteraction on record

Description

Reduces systemic exposure and peak plasma concentration of olmesartan. Consider administering olmesartan at least 4 hours before colesevelam hydrochloride dose.

Mechanism

Bile acid sequestrating agent reduces absorption of olmesartan

Source: NLP:olmesartan medoxomil-hydrochlorothiazide