Colesevelam Hydrochloride + Olmesartan Medoxomil Amlodipine Besylate Hydrochlorothiazide Interaction

Moderateinteraction on record

Description

Reduces systemic exposure and peak plasma concentration of olmesartan. Administer olmesartan at least 4 hours before colesevelam hydrochloride.

Mechanism

Bile acid sequestrant reduces absorption of olmesartan

Source: NLP:olmesartan medoxomil, amlodipine besylate and hydrochlorothiazide