Codeine Phosphate And Chlorpheniramine Maleate + Phenytoin Interaction

Majorinteraction on record

Description

Avoid concomitant use; may increase phenytoin levels and cause phenytoin toxicity. Chlorpheniramine may inhibit hepatic metabolism of phenytoin.

Mechanism

Chlorpheniramine may inhibit hepatic metabolism of phenytoin

Source: NLP:codeine phosphate and chlorpheniramine maleate