Clopidogrel Bisulfate + Rifampin Interaction

Majorinteraction on record

Description

Strong CYP2C19 inducer that increases clopidogrel active metabolite levels and platelet inhibition, potentiating risk of bleeding. Avoid concomitant use.

Mechanism

CYP2C19 induction increases clopidogrel active metabolite formation

Source: NLP:clopidogrel bisulfate