Cisplatin + Furosemide Benzalkonium Chloride Interaction

Majorinteraction on record

Description

Risk of ototoxic effects if cisplatin and furosemide are given concomitantly. Nephrotoxicity may be enhanced if furosemide is not given in lower doses with positive fluid balance.

Mechanism

Ototoxicity and enhanced nephrotoxicity

Source: NLP:furosemide, benzalkonium chloride