Cimetidine + Venlafaxine Hcl Er Interaction
Moderateinteraction on record
Description
Inhibits first-pass metabolism of venlafaxine, increasing AUC and Cmax by about 60%. Caution advised in patients with pre-existing hypertension, elderly patients, and those with hepatic dysfunction.
Mechanism
Inhibition of first-pass metabolism
Source: NLP:venlafaxine hydrochloride, extended release