Cimetidine + Midazolam Interaction

Moderateinteraction on record

Description

Inhibits P450-3A4 enzyme system, increasing midazolam steady-state concentration and prolonging sedation by decreasing plasma clearance.

Mechanism

P450-3A4 enzyme inhibition

Source: NLP:midazolam

Related drug profiles

All Cimetidine interactions →All Midazolam interactions →
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