Cholestyramine Light + Mycophenolate Mofetil Interaction

Majorinteraction on record

Description

Cholestyramine decreases MPA AUC by approximately 40%. Not recommended for concomitant use due to interruption of enterohepatic recirculation.

Mechanism

Binding of recirculating MPAG in intestine, interrupting enterohepatic recirculation

Source: NLP:mycophenolate mofetil