Carbamazepine + Tramadol Hydrochloride Interaction

Contraindicatedinteraction on record

Description

CYP3A4 inducer that significantly reduces tramadol analgesic effect and increases seizure risk. Concomitant use is not recommended.

Mechanism

Induction of CYP3A4-mediated metabolism of tramadol; tramadol lowers seizure threshold

Source: NLP:tramadol hydrochloride

Related drug profiles

All Carbamazepine interactions →All Tramadol Hydrochloride interactions →
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