Carbamazepine + Ifosfamide Interaction
Moderateinteraction on record
Description
CYP3A4 inducer may increase metabolism of ifosfamide to active metabolites and increase formation of neurotoxic/nephrotoxic chloroacetaldehyde. Monitor for toxicities and consider dose adjustment.
Mechanism
CYP3A4 induction increases ifosfamide metabolism
Source: NLP:ifosfamide