Captopril And Hydrochlorothiazide + Amiloride Interaction
Majorinteraction on record
Description
May cause significant increase in serum potassium. Should only be given for documented hypokalemia and with caution due to risk of hyperkalemia.
Mechanism
Captopril decreases aldosterone production; amiloride is potassium-sparing
Source: NLP:captopril and hydrochlorothiazide