Cannabidiol + Rifampin Interaction

Moderateinteraction on record

Description

Strong CYP3A4 and CYP2C19 inducer decreases cannabidiol and 7-OH-CBD plasma concentrations by approximately 32% and 63%, potentially reducing EPIDIOLEX efficacy.

Mechanism

CYP3A4 and CYP2C19 induction

Source: NLP:cannabidiol