Buprenorphine Hydrochloride And Naloxone Hydrochloride Dihyd + Sedating Antihistamines Interaction
Majorinteraction on record
Description
Increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Mechanism
Additive pharmacologic effects
Source: NLP:buprenorphine hydrochloride and naloxone hydrochloride dihydrate