Blinatumomab + Cyclosporine Interaction
Moderateinteraction on record
Description
BLINATUMOMAB causes transient cytokine release that may suppress CYP450 enzymes, potentially increasing cyclosporine concentrations. Monitor drug levels during first 9 days of first cycle and first 2 days of second cycle.
Mechanism
CYP450 enzyme suppression due to cytokine release
Source: NLP:blinatumomab