Bisoprolol Fumarate And Hydrochlorothiazide + Guanethidine Interaction
Majorinteraction on record
Description
Catecholamine-depleting drug that with bisoprolol's beta-adrenergic blocking action may produce excessive reduction of sympathetic activity. Close monitoring required.
Mechanism
Additive beta-adrenergic blocking action
Source: NLP:bisoprolol fumarate and hydrochlorothiazide