Belatacept + Mycophenolate Mofetil Interaction
Moderateinteraction on record
Description
Monitor for need to adjust MMF dosage when switching between cyclosporine and belatacept, as cyclosporine decreases MPA exposure while belatacept does not. May require higher MMF dosage after switching to cyclosporine or lower dosage after switching from cyclosporine to belatacept.
Mechanism
Cyclosporine decreases mycophenolic acid exposure by preventing enterohepatic recirculation; belatacept does not have this effect
Source: NLP:belatacept