Azathioprine + Ribavirin Interaction
Majorinteraction on record
Description
Concomitant use induces severe pancytopenia and increases risk of azathioprine-related myelotoxicity through interference with IMDH metabolic pathway.
Mechanism
Ribavirin interferes with inosine monophosphate dehydrogenase (IMDH), a required metabolic pathway for azathioprine
Source: NLP:ribavirin