Atenolol And Chlorthalidone + Epinephrine Interaction

Majorinteraction on record

Description

Patients with history of anaphylaxis may have more severe reactions and may be unresponsive to usual doses of epinephrine during beta-blocker therapy.

Mechanism

Beta-blocker-induced blunting of sympathetic response

Source: NLP:atenolol and chlorthalidone