Atazanavir And Cobicistat + Repaglinide Interaction
Majorinteraction on record
Description
Repaglinide is highly dependent on CYP2C8 for clearance with narrow therapeutic index. EVOTAZ use is not recommended with repaglinide due to potential for increased plasma concentrations.
Mechanism
CYP2C8 inhibition by atazanavir
Source: NLP:atazanavir and cobicistat