Atazanavir + Lansoprazole Amoxicillin Clarithromycin Interaction

Majorinteraction on record

Description

Decreased exposure of atazanavir when used concomitantly with lansoprazole may reduce antiviral effect and promote development of drug resistance.

Mechanism

PPI decreases exposure of antiretroviral drug

Source: NLP:lansoprazole, amoxicillin, clarithromycin