Asenapine Maleate + Paroxetine Interaction
Moderateinteraction on record
Description
CYP2D6 substrate and inhibitor that increases paroxetine exposure 2-fold when combined with SAPHRIS. Paroxetine dose should be reduced by half.
Mechanism
Enhanced inhibition of paroxetine metabolism via CYP2D6
Source: NLP:asenapine maleate