Anakinra + Avutometinib Potassium And Defactinib Hydrochloride Interaction
Majorinteraction on record
Description
Concomitant use decreases defactinib exposure, which may reduce the effectiveness of the drug combination. Avoid concomitant use.
Mechanism
Gastric acid reduction decreases defactinib exposure
Source: NLP:avutometinib potassium and defactinib hydrochloride