Amlodipine And Benazepril Hydrochloride + Ibuprofen Interaction
Majorinteraction on record
Description
NSAIDs with benazepril may result in deterioration of renal function and acute renal failure, especially in elderly or volume-depleted patients. Antihypertensive effect may be attenuated.
Mechanism
NSAID inhibits renal prostaglandin-mediated vasodilation
Source: NLP:amlodipine besylate and benazepril hydrochloride