Amiloride Hydrochloride + Indomethacin Interaction

Moderateinteraction on record

Description

May reduce diuretic, natriuretic, and antihypertensive effects of amiloride HCl. Both agents may increase serum potassium levels; potential effects on potassium kinetics and renal function should be considered.

Mechanism

NSAIDs reduce diuretic efficacy; both increase serum potassium

Source: NLP:amiloride hydrochloride