Aliskiren + Valsartan And Hydrochlorothiazide Interaction
Contraindicatedinteraction on record
Description
Dual blockade of RAS associated with increased risks of hypotension, hyperkalemia, and renal failure. Contraindicated in patients with diabetes and should be avoided in renal impairment.
Mechanism
Dual RAS blockade increases risks of adverse effects compared to monotherapy
Source: NLP:valsartan and hydrochlorothiazide