Abacavir Sulfate Dolutegravir Sodium Lamivudine + Etravirine Interaction
Majorinteraction on record
Description
Etravirine significantly reduced plasma concentrations of dolutegravir, potentially reducing therapeutic effect. Effect may be mitigated by coadministration with lopinavir/ritonavir or darunavir/ritonavir.
Mechanism
Induction of UGT1A1 and/or CYP3A enzymes
Source: NLP:abacavir sulfate, dolutegravir sodium, lamivudine