54 interactions on record
Serious dose-related cardiac arrhythmias may occur if preparations containing vasoconstrictor are used during or following administration.
Source: NLP:betamethasone sodium phosphate and betamethasone acetate, bupivacaine hydrochloride, povidine iodine
Serious dose-related cardiac arrhythmias may occur if preparations containing vasoconstrictor are used during or after administration.
Source: NLP:bupivacaine hydrochloride
Serious dose-related cardiac arrhythmias may occur if MARCAINE WITH EPINEPHRINE is used during or following potent inhalation anesthetic administration.
Source: NLP:bupivacaine hydrochloride and epinephrine bitartrate
Concomitant use increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Source: NLP:buprenorphine and naloxone
Concomitant use increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Source: NLP:buprenorphine hcl
General anesthetics may enhance effects causing increased CNS depression.
Source: NLP:butalbital, acetaminophen, and caffeine
Butalbital causes increased CNS depression when combined with general anesthetics.
Source: NLP:butalbital, aspirin, and caffeine
Administration with nitrous oxide/oxygen for >30 minutes may prolong duration of action and potentiate neuromuscular blockade. Monitor with peripheral nerve stimulator.
Source: NLP:cisatracurium besylate
Serious dose-related cardiac arrhythmias may occur if preparations containing vasoconstrictor epinephrine are used during or following potent inhalation anesthetic administration.
Source: NLP:dexamethasone sodium phosphate, bupivacaine hydrochloride, povidine iodine
Concomitant use may increase risk of sudden blood pressure and heart rate increase during surgery. Avoid use on day of surgery.
Source: NLP:dexmethylphenidate hydrochloride
Concurrent use may result in arrhythmias.
Source: NLP:diethylpropion hydrochloride
Depressed cardiac contractility, conductivity, and automaticity as well as vascular dilation.
Source: NLP:diltiazem hydrochloride
Can sensitize the myocardium to dopamine effects and produce ventricular arrhythmias and hypertension.
Source: NLP:dopamine hydrochloride
Hyaluronidase hastens onset and shortens duration of effect of local anesthetics, increasing incidence of systemic reactions due to wider spread and increased absorption.
Source: NLP:hyaluronidase
Additive CNS depression increasing risk of hypotension, respiratory depression, profound sedation, coma, and death.
Source: NLP:levorphanol tartrate
Serious dose-related cardiac arrhythmias may occur if lidocaine solutions containing epinephrine are used during or following administration.
Source: NLP:lidocaine hydrochloride
Serious dose-related cardiac arrhythmias may occur when epinephrine-containing preparations are used during or following potent inhalation anesthetics.
Source: NLP:lidocaine hydrochloride and epinephrine
Produces increased CNS-depressant effects including respiratory depression and sedation.
Source: NLP:lorazepam
Anesthesia may potentiate the action of Mecamylamine HCl.
Source: NLP:mecamylamine hydrochloride
Serious cardiac arrhythmias may occur if preparations containing vasoconstrictors are employed during or following their administration.
Source: NLP:mepivacaine hydrochloride
CNS depressant effect increases risk of respiratory depression, profound sedation, coma, and death.
Source: NLP:methadone hydrochloride
Concomitant use may increase risk of sudden blood pressure and heart rate increase during surgery. Avoid use on day of surgery.
Source: NLP:methylphenidate
Concomitant use may increase risk of sudden blood pressure and heart rate increase during surgery. Avoid use on day of surgery.
Source: NLP:methylphenidate hydrochloride
Serious dose-related cardiac arrhythmias may occur if preparations containing epinephrine are used during or following potent inhalation anesthetics.
Source: NLP:methylprednisolone acetate, lidocaine hydrochloride, bupivacaine hydrochloride, povidine iodine, isopropyl alcohol
Exaggeration of hypotension induced by general anesthetics when administered concurrently with nadolol.
Source: NLP:nadolol
Concomitant use increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Source: NLP:nalbuphine hydrochloride
Concomitant use increases risk of hypotension, respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Source: NLP:pentazocine and naloxone
Promethazine may increase, prolong, or intensify the sedative action of general anesthetics; avoid or use reduced dosage.
Source: NLP:promethazine hydrochloride
Promethazine may increase, prolong, or intensify sedative action of general anesthetics.
Source: NLP:promethazine hydrochloride and dextromethorphan hydrobromide
Should be used cautiously or avoided during pyridostigmine treatment due to interference with neuromuscular transmission.
Source: NLP:pyridostigmine bromide
May enhance rocuronium bromide activity and neuromuscular blockade.
Source: NLP:rocuronium bromide
Produces additive CNS-depressant effects when co-administered with temazepam.
Source: NLP:temazepam
Concomitant administration associated with erythema, histamine-like flushing, and anaphylactoid reactions.
Source: NLP:vancomycin hydrochloride
Both inhalation anesthetics and verapamil depress cardiovascular activity by decreasing calcium ion movement. Concurrent use requires careful titration to avoid excessive cardiovascular depression.
Source: NLP:verapamil hydrochloride
Possibility of additive or potentiating effect with CNS depressants.
Source: NLP:apraclonidine
Possibility of additive or potentiating CNS depressant effect with brimonidine.
Source: NLP:brimonidine
CNS depressant with potential for additive or potentiating effect when used with brimonidine tartrate ophthalmic solution.
Source: NLP:brimonidine tartrate
CNS depressant with possibility of additive or potentiating effect on central nervous system depression.
Source: NLP:brimonidine tartrate and timolol maleate
Toxic effects are additive; concomitant use requires caution with monitoring for neurologic and cardiovascular effects from local anesthetic systemic toxicity.
Source: NLP:bupivacaine
General anesthetics may enhance the effects of butalbital and acetaminophen, causing increased CNS depression.
Source: NLP:butalbital and acetaminophen
Anesthetics may result in additive or potentiating CNS depressant effects with YUVEZZI.
Source: NLP:carbachol and brimonidine tartrate
May potentiate or be potentiated by diazepam action. Careful consideration should be given when combining.
Source: NLP:diazepam
Additive or potentiating CNS depressant effects; droperidol dose should be reduced when used concomitantly.
Source: NLP:droperidol
CNS depressants that may be potentiated by haloperidol decanoate; monitor for combined CNS depression effects.
Source: NLP:haloperidol decanoate
May suppress the flare responses to histamine and should be avoided at skin test sites.
Source: NLP:histamine
Additive CNS depressant effects; reduced dosage of hydromorphone recommended to avoid excessive effects.
Source: NLP:hydromorphone hydrochloride
When used concomitantly with other local anesthetic products, the total amount absorbed from all formulations must be considered to avoid toxicity.
Source: NLP:lidocaine 5%
When used concurrently with other local anesthetic products, total absorbed amount from all formulations must be considered to avoid toxicity.
Source: NLP:menthol 5%, lidocaine 4%
Additive CNS depressant effects may occur; dosage adjustment needed when used concomitantly with magnesium sulfate.
Source: NLP:magnesium sulfate
Phenylephrine may potentiate the cardiovascular depressant effects of inhalation anesthetic agents.
Source: NLP:phenylephrine hydrochloride
Promethazine may increase, prolong, or intensify sedative action; agents should be avoided or administered in reduced dosage.
Source: NLP:promethazine hydrochloride and phenylephrine hydrochloride
Hypotensive effect of sodium nitroprusside is augmented by inhaled anesthetics.
Source: NLP:sodium nitroprusside
Effects of preanesthetic and anesthetic agents may be potentiated when given with triamterene.
Source: NLP:triamterene
Concomitant administration has been associated with erythema and histamine-like flushing.
Source: NLP:vancomycin