Ergotamine Interactions

Do not use almotriptan malate and ergotamine within 24 hours of each other due to risk of prolonged vasospastic reactions.

Source: NLP:almotriptan malate

Ergotamine-containing drugs cause prolonged vasospastic reactions. Use within 24 hours of eletriptan hydrobromide is contraindicated due to additive effects.

Source: NLP:eletriptan hydrobromide

Co-administration associated with acute ergot toxicity characterized by vasospasm and ischemia of extremities and other tissues including central nervous system.

Source: NLP:erythromycin

Coadministration associated with acute ergot toxicity characterized by vasospasm and ischemia of extremities and central nervous system.

Source: NLP:erythromycin ethylsuccinate

Co-administration associated with acute ergot toxicity characterized by vasospasm and ischemia of central nervous system and tissues.

Source: NLP:erythromycin lactobionate

Coadministration is contraindicated. Itraconazole increases plasma concentrations of ergot alkaloids, potentially increasing pharmacologic effects and adverse reactions.

Source: NLP:itraconazole

Coadministration of ketoconazole with ergotamine is contraindicated.

Source: NLP:ketoconazole

Mifepristone increases ergotamine exposure; concomitant use is contraindicated due to narrow therapeutic range.

Source: NLP:mifepristone

Nitroglycerin markedly decreases first-pass metabolism of ergotamine, increasing bioavailability. Ergotamine can precipitate angina pectoris. Avoid concomitant use.

Source: NLP:nitroglycerin

Ergot-containing drugs cause prolonged vasospastic reactions. Use within 24 hours of rizatriptan benzoate is contraindicated due to potentially additive vasospastic effects.

Source: NLP:rizatriptan benzoate

Ergotamine-containing drugs cause prolonged vasospastic reactions that may be additive with sumatriptan. Use within 24 hours of each other is contraindicated.

Source: NLP:sumatriptan

Ergotamine-containing drugs cause prolonged vasospastic reactions; additive effects contraindicate use within 24 hours of sumatriptan succinate.

Source: NLP:sumatriptan succinate

Ergot-containing drugs cause prolonged vasospastic reactions. Coadministration within 24 hours is contraindicated due to additive effects.

Source: NLP:sumatriptan and naproxen sodium

Ergotamine-containing drugs cause prolonged vasospastic reactions that may be additive with zolmitriptan. Use within 24 hours of each other is contraindicated.

Source: NLP:zolmitriptan

Deferasirox may induce CYP3A4 resulting in decreased ergotamine concentration. Monitor for reduced effectiveness.

Source: NLP:deferasirox

Nitroglycerin decreases first-pass metabolism of ergotamine, increasing bioavailability. Ergotamine may precipitate angina pectoris; monitor or avoid concomitant use.

Source: NLP:nitroglycerin lingual

In vitro data of benzodiazepines suggest possible drug interaction with triazolam. Caution recommended.

Source: NLP:triazolam