Cns Depressants Interactions

Increased risk of CNS depression; avoid concomitant use and monitor for adverse reactions.

Source: NLP:metoclopramide hydrochloride

Other CNS depressants may enhance effects causing increased CNS depression.

Source: NLP:butalbital, acetaminophen, and caffeine

Butalbital causes increased CNS depression when combined with other CNS depressants.

Source: NLP:butalbital, aspirin, and caffeine

Potentiate sedating effects of clonidine. Avoid use.

Source: NLP:clonidine hydrochloride

Concomitant use increases risk of sedation and somnolence; effects may be potentiated.

Source: NLP:clobazam

Sedative effects of CNS depressants may be potentiated when taken with doxepin.

Source: NLP:doxepin

Sedative effects of CNS depressants may be potentiated when taken with doxepin.

Source: NLP:doxepin hydrochloride

Additive CNS effects (dizziness, confusion, sedation, somnolence) may occur when taken concomitantly with dronabinol.

Source: NLP:dronabinol

Haloperidol may potentiate CNS depressants including anesthetics, opioids, and alcohol.

Source: NLP:haloperidol decanoate

Concurrent use may result in increased CNS depression; monitor accordingly.

Source: NLP:meclizine hydrochloride

Concomitant use may increase risk of sedation and respiratory depression. Closely monitor for signs of respiratory depression and sedation, particularly during treatment initiation and dosage increases.

Source: NLP:metaxalone

Increased risk of sedation and respiratory depression with concomitant use. Closely monitor for adverse effects.

Source: NLP:phenobarbital sodium

Should be used with extreme caution due to potential CNS depression and cognitive/neuropsychiatric adverse reactions.

Source: NLP:topiramate

Triazolam produces additive CNS depressant effects when co-administered with other CNS depressants. Dosage and duration should be limited during concomitant use.

Source: NLP:triazolam