Thiazides Interactions

Concomitant administration of thiazides with calcitriol causes hypercalcemia due to reduction of calcium excretion in urine. Precaution required.

Source: NLP:calcitriol

Increased incidence of thrombocytopenia with purpura reported in elderly patients concurrently receiving thiazides.

Source: NLP:sulfamethoxazole and trimethoprim

Thiazides produce hyperglycemia and may lead to loss of blood glucose control in patients receiving Acarbose. Close observation for loss of glucose control is recommended.

Source: NLP:acarbose

Concomitant administration may cause hypercalcemia due to thiazide-induced reduction in urinary calcium excretion. More frequent serum calcium monitoring required.

Source: NLP:calcifediol

Concomitant use may cause hypercalcemia; precaution should be taken when coadministration is necessary.

Source: NLP:calcitriol capsules 0.25 mcg

Some thiazides are urinary alkalinizing agents that increase blood levels and potentiate amphetamine action. Co-administration should be avoided.

Source: NLP:dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate and amphetamine sulfate

Some thiazides act as urinary alkalinizing agents, decreasing urinary excretion and potentiating amphetamine effects.

Source: NLP:dextroamphetamine sulfate

Concomitant administration may potentiate the hyperglycemic and hyperuricemic effects of diazoxide.

Source: NLP:diazoxide

NSAIDs can reduce natriuretic effect of thiazides. Monitor patient for signs of renal failure and assure diuretic efficacy.

Source: NLP:diclofenac sodium

Diflunisal can reduce the natriuretic effect of thiazides in some patients.

Source: NLP:diflunisal

Diuretic that may produce hyperglycemia and lead to loss of glycemic control; monitor closely.

Source: NLP:empagliflozin, metformin hydrochloride

Thiazides may produce hyperglycemia and lead to loss of control of glyburide. Patients should be closely observed for loss of control.

Source: NLP:glyburide

May reduce glucose-lowering effect of glimepiride, leading to worsening glycemic control.

Source: NLP:glimepiride

Thiazide diuretics may produce hyperglycemia and lead to loss of glycemic control. Patient should be observed closely for loss of control when initiated or withdrawn.

Source: NLP:glipizide

Thiazide diuretics tend to produce hyperglycemia and may lead to loss of glycemic control.

Source: NLP:glyburide and metformin hydrochloride

Ibuprofen can reduce the natriuretic effect of thiazide diuretics. Patient should be observed for signs of renal failure and to assure diuretic efficacy.

Source: NLP:ibuprofen

Ketorolac can reduce the natriuretic effect of thiazide diuretics. Close observation for signs of renal failure and diuretic efficacy is needed during concomitant therapy.

Source: NLP:ketorolac tromethamine

Thiazide diuretics may produce hyperglycemia and lead to loss of glycemic control. Close monitoring of glycemic control is recommended.

Source: NLP:linagliptin and metformin hydrochloride

NSAIDs may reduce natriuretic effect; monitor closely for renal failure and ensure diuretic efficacy during concomitant use.

Source: NLP:meloxicam

Diuretics that produce hyperglycemia and may lead to loss of glycemic control; monitor blood glucose.

Source: NLP:metformin hydrochloride

Diuretics that produce hyperglycemia and may lead to loss of glycemic control during metformin therapy.

Source: NLP:metformin hydrochloride extended-release tablets

Diuretic that may produce hyperglycemia and lead to loss of glycemic control with metformin.

Source: NLP:metformin hydrochloride tablet

Nabumetone can reduce the natriuretic effect of thiazide diuretics. Patient should be observed for signs of renal failure and diuretic efficacy during concomitant therapy.

Source: NLP:nabumetone

Naproxen can reduce the natriuretic effect of thiazide diuretics. Monitor closely for signs of renal failure.

Source: NLP:naproxen

Salsalate can reduce the natriuretic effect of thiazides in some patients. Close observation for renal failure and diuretic efficacy is recommended.

Source: NLP:salsalate

Diuretic that produces hyperglycemia and may lead to loss of glycemic control. Monitor blood glucose closely.

Source: NLP:sitagliptin and metformin hydrochloride

Sulindac can reduce natriuretic effect of thiazides; patient should be observed for signs of renal failure and to assure diuretic efficacy.

Source: NLP:sulindac