Alpha-Blockers Interactions

Hyaluronidase should not be used to enhance the dispersion and absorption of alpha agonist drugs.

Source: NLP:hyaluronidase

Concomitant use can cause significant additive blood pressure reduction leading to symptomatic hypotension (dizziness, lightheadedness, fainting). Caution is advised when co-administered.

Source: NLP:avanafil

Potential additive blood pressure-lowering effects. Initiate sildenafil at lowest dose after patients are stable on alpha-blocker therapy.

Source: NLP:sildenafil citrate

Pharmacodynamic interactions expected but not fully determined. Concomitant use is not recommended due to potential additive effects.

Source: NLP:silodosin

Caution advised when tadalafil is coadministered with alpha-blockers. Both are vasodilators with blood-pressure-lowering effects, resulting in additive hypotensive effects.

Source: NLP:tadalafil

Should not be used in combination with alfuzosin. Pharmacokinetic and pharmacodynamic interactions may be expected.

Source: NLP:alfuzosin hydrochloride

Antagonize peripheral vasoconstriction caused by high-dose dopamine but do not antagonize renal and mesenteric vasodilation.

Source: NLP:dopamine hydrochloride

Alpha-blockers may cause additive blood pressure-lowering effects with sildenafil; use caution and initiate sildenafil at lowest dose in stable patients.

Source: NLP:sildenafil