Acidifying Agents Interactions

May cause hypoglycemia through additive effects when dosage exceeds maximum recommended daily amount.

Source: NLP:butalbital, aspirin, and caffeine

Concomitant use may increase the risk of bleeding. Avoid concomitant use when possible and monitor closely for bleeding.

Source: NLP:caplacizumab

Antianxiety agents potentiate CNS-depressant action of clonazepam.

Source: NLP:clonazepam

Anticholinergics antagonize antiglaucoma agents and may increase intraocular pressure. Use of dicyclomine hydrochloride in patients with glaucoma is not recommended.

Source: NLP:dicyclomine hydrochloride

Coadministration increases the risk of bleeding.

Source: NLP:eptifibatide

Linezolid has potential for interaction with adrenergic agents; monitoring and caution required.

Source: NLP:linezolid

Increased risk of serotonin syndrome when co-administered with lithium. Monitor for signs and symptoms; consider discontinuation if syndrome occurs.

Source: NLP:lithium carbonate

Disturbances of blood glucose including hyperglycemia and hypoglycemia reported. Carefully monitor blood glucose during co-administration.

Source: NLP:moxifloxacin hydrochloride

Naproxen increases bleeding risk when used with antiplatelet agents. Monitor for signs of bleeding.

Source: NLP:naproxen

Concomitant use may result in tachycardia, arrhythmias, serious hypertensive response and possible stroke.

Source: NLP:promethazine, phenylephrine, codeine

Should be used cautiously or avoided during pyridostigmine treatment due to interference with neuromuscular transmission.

Source: NLP:pyridostigmine bromide

Antiplatelet agents potentiate bleeding risk when combined with sumatriptan and naproxen sodium. Monitor for bleeding.

Source: NLP:sumatriptan and naproxen sodium

Increased risk of renal toxicity when used with torsemide.

Source: NLP:torsemide

Possibility of additive effects when epinephrine is administered with other sympathomimetic agents.

Source: NLP:adrenalin (epinephrine)

Agents with anticholinergic properties may potentiate the anticholinergic-like side effects of amantadine.

Source: NLP:amantadine

May potentiate the anticholinergic-like side effects of amantadine hydrochloride.

Source: NLP:amantadine hydrochloride

Interaction possible when given with amitriptyline; see text for clinical details.

Source: NLP:amitriptyline hydrochloride

Lower blood levels and efficacy of amphetamines. Dose adjustment may be needed based on clinical response.

Source: NLP:amphetamine extended-release

Concurrent use may enhance potential for renal toxicity, bronchospasm, and hypotension. Should be given concomitantly with caution.

Source: NLP:amphotericin b

Concomitant administration may increase the risk of hypoglycemia.

Source: NLP:benazepril hydrochloride

Corticosteroids may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:betamethasone acetate and betamethasone sodium phosphate

Antihistamine component has additive CNS depressant effects with antianxiety agents.

Source: NLP:brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide

Antihistamines have additive effects with antianxiety agents and other CNS depressants.

Source: NLP:brompheniramine maleate, pseudoephedrine hydrochloride,

Symptomatic postural hypotension may occur; dose adjustment of antihypertensive drug may be required.

Source: NLP:carbidopa, levodopa and entacapone

Cevimeline might interfere with desirable antimuscarinic effects of drugs used concomitantly.

Source: NLP:cevimeline hydrochloride

Dosage adjustment of oral antidiabetic drugs may be required when used concurrently with chlorothiazide.

Source: NLP:chlorothiazide

Higher dosages of oral hypoglycemic agents may be required during chlorthalidone administration due to altered glucose control.

Source: NLP:chlorthalidone

Plasma levels of anticonvulsant agents may become subtherapeutic during cisplatin therapy, potentially reducing anticonvulsant efficacy.

Source: NLP:cisplatin

Concomitant use may potentiate risk of bleeding. Inform patients of increased bleeding risk.

Source: NLP:citalopram hydrobromide

Immunosuppressive agents may suppress the response to the skin test.

Source: NLP:coccidioides immitis spherule-derived skin test antigen

Antianxiety agents may have additive CNS depressant effects with cyproheptadine.

Source: NLP:cyproheptadine hydrochloride

Corticosteroids may increase blood glucose concentration, requiring dosage adjustments of antidiabetic agents.

Source: NLP:depo-medrol, lidocaine, isopropyl alcohol

Dexamethasone may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:dexamethasone

Dexamethasone may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:dexamethasone 1.5 mg

Dexamethasone may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:dexamethasone intensol

Lower blood levels and efficacy of amphetamines. Dose adjustment based on clinical response may be needed.

Source: NLP:dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate

Additive effects possible when epinephrine is administered with other sympathomimetic agents.

Source: NLP:adrenalin(r)

Additional reductions in blood pressure may occur when epoprostenol is administered with antihypertensive agents.

Source: NLP:epoprostenol

Dosage adjustment of oral antidiabetic drugs may be required when used concurrently with hydrochlorothiazide.

Source: NLP:hydrochlorothiazide

Omega-3 fatty acids may prolong bleeding time. Monitor patients for bleeding when icosapent ethyl is used concomitantly with antiplatelet agents.

Source: NLP:icosapent ethyl

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Source: NLP:insulin degludec

Potential for additive interaction with anticholinergic medications due to ipratropium's anticholinergic properties, despite minimal systemic absorption.

Source: NLP:ipratropium bromide and albuterol sulfate

Disturbances of blood glucose including hyperglycemia and hypoglycemia have been reported. Careful monitoring of blood glucose is recommended.

Source: NLP:levofloxacin

Addition of levothyroxine to antidiabetic therapy may result in increased antidiabetic agent requirements. Careful monitoring of diabetic control is recommended.

Source: NLP:levothyroxine sodium anhydrous

Urinary acidifying agents decrease blood levels and efficacy of amphetamines. Dose increase may be needed based on clinical response.

Source: NLP:lisdexamfetamine

Urinary acidifying agents lower blood levels and efficacy of amphetamines. Dose adjustment may be needed.

Source: NLP:lisdexamfetamine dimesylate

Concomitant administration with lisinopril may cause increased blood-glucose-lowering effect with risk of hypoglycemia.

Source: NLP:lisinopril

Corticosteroids may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:ammonia, lidocaine hydrochloride, triamcinolone acetonide, povidone-iodine

Corticosteroids may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:methylprednisolone sodium succinate

May affect the results of the metyrapone test. Consider withdrawing if possible before testing.

Source: NLP:metyrapone

Additional adrenergic drugs may potentiate sympathetic effects of formoterol. Use with caution.

Source: NLP:mometasone furoate and formoterol fumarate dihydrate

May cause disturbances in blood glucose including hyperglycemia and hypoglycemia. Carefully monitor blood glucose levels.

Source: NLP:moxifloxacin

Moxifloxacin may cause blood glucose disturbances including hyperglycemia and hypoglycemia. Carefully monitor blood glucose during concomitant use.

Source: NLP:moxifloxacin hydrochloride tablets, 400 mg

Nadolol may cause hypoglycemia or hyperglycemia; adjust dosage of antidiabetic drug accordingly.

Source: NLP:nadolol

Octreotide inhibits glucagon secretion; blood glucose levels should be monitored and anti-diabetic treatment adjusted accordingly.

Source: NLP:octreotide acetate

Enhanced antihypertensive effect when combined with olanzapine.

Source: NLP:olanzapine

Enhanced antihypertensive effect may occur with concurrent use.

Source: NLP:olanzapine and fluoxetine

Addition of other antihypertensive agents to prazosin causes additive hypotensive effect. Introduce cautiously and retitrate prazosin based on clinical response.

Source: NLP:prazosin hydrochloride

Corticosteroids may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic agents.

Source: NLP:prednisolone sodium phosphate

Corticosteroids may increase blood glucose concentrations, requiring dosage adjustments of antidiabetic medications.

Source: NLP:prednisone

Phenylephrine with bronchodilator sympathomimetic agents may cause tachycardia or other arrhythmias.

Source: NLP:promethazine hydrochloride and phenylephrine hydrochloride

Quetiapine may enhance the effects of antihypertensive agents due to its potential for inducing hypotension.

Source: NLP:quetiapine fumarate er

Concurrent use may potentiate the risk of bleeding.

Source: NLP:sertraline hydrochloride

Hypotensive effect of sodium nitroprusside is augmented by negative inotropic agents.

Source: NLP:sodium nitroprusside

Hypoglycemic agents may require dose adjustment when used concomitantly with somatropin.

Source: NLP:somatropin

Concomitant use not recommended; combined effect on cardiovascular system may be deleterious. Exception: aerosol bronchodilators of adrenergic-stimulant type may be used for acute bronchospasm relief.

Source: NLP:terbutaline sulfate

Concomitant use may cause increased blood glucose lowering effect with greater risk of hypoglycemia.

Source: NLP:trandolapril

Corticosteroids may increase blood glucose; dosage adjustments of antidiabetics may be required.

Source: NLP:triamcinolone acetonide

Corticosteroids may increase blood glucose concentrations; dosage adjustments of antidiabetic agents may be required.

Source: NLP:triamcinolone acetonide extended-release injectable suspension

Immunosuppressive agents may depress or suppress reactivity to tuberculin test; reduced reactivity may persist for 5-6 weeks after discontinuation.

Source: NLP:tuberculin purified protein derivative

Hydrochlorothiazide may increase blood glucose; dosage adjustment of antidiabetic drug may be required.

Source: NLP:valsartan and hydrochlorothiazide

Vardenafil may add to blood pressure lowering effects of antihypertensive medications.

Source: NLP:vardenafil

Vardenafil hydrochloride may add to the blood pressure lowering effects of antihypertensive agents.

Source: NLP:vardenafil hydrochloride

Concurrent use may potentiate bleeding risk. Inform patients of increased bleeding risk.

Source: NLP:vilazodone hydrochloride

Ziprasidone may enhance the effects of antihypertensive agents due to its potential for inducing hypotension.

Source: NLP:ziprasidone

Ziprasidone may enhance the effects of certain antihypertensive agents due to its potential for inducing hypotension.

Source: NLP:ziprasidone hcl

Ziprasidone may enhance the hypotensive effects of antihypertensive agents due to its potential for inducing hypotension.

Source: NLP:ziprasidone mesylate

No well-controlled studies have been performed on patients taking antiovulatory agents. Physician must use judgment and evaluate patients prior to initiating treatment.

Source: NLP:(sotradecol) sodium tetradecyl sulfate

No well-controlled studies performed; physician must evaluate patients taking antiovulatory drugs before initiating Sotradecol treatment.

Source: NLP:sodium tetradecyl sulfate

Safety of ustekinumab in combination with immunosuppressive agents has not been evaluated in plaque psoriasis trials.

Source: NLP:ustekinumab-ttwe