May alter serum T4 and T3 transport or metabolism affecting levothyroxine efficacy.
Source: NLP:levothyroxine sodium
Hydantoins Interactions
2 interactions on record
Hydantoins + Liothyronine SodiumModerate
May cause protein binding site displacement. Phenytoin reduces serum protein binding of thyroid hormones, with total and FT4 reduced 20-40%, but most patients remain clinically euthyroid. Closely monitor thyroid parameters.
Source: NLP:liothyronine sodium