Nitrates Interactions

Avanafil is contraindicated with organic nitrates. Avanafil potentiates the hypotensive effect of nitrates, which can be life-threatening. At least 12 hours must elapse after avanafil before nitrate administration.

Source: NLP:avanafil

Administration of nitrates within 48 hours after the last dose of OPSYNVI is contraindicated.

Source: NLP:macitentan and tadalafil

Co-administration with nitrates is contraindicated because of hypotension.

Source: NLP:riociguat

Administration of sildenafil with nitrates is contraindicated. Sildenafil potentiates the hypotensive effects of nitrates.

Source: NLP:sildenafil

Administration of sildenafil with nitrates is contraindicated. Sildenafil potentiates the hypotensive effects of nitrates through effects on the nitric oxide/cGMP pathway.

Source: NLP:sildenafil citrate

Administration of tadalafil to patients using any form of organic nitrate is contraindicated. Tadalafil potentiates the hypotensive effect of nitrates.

Source: NLP:tadalafil

Concomitant use is contraindicated. Vardenafil potentiates blood pressure lowering effects and increases heart rate when taken within 8 hours of nitrates.

Source: NLP:vardenafil

Concomitant use of vardenafil hydrochloride and nitrates is contraindicated. Vardenafil potentiates the blood pressure lowering effects of nitrates.

Source: NLP:vardenafil hydrochloride

Increased risk of hypotension, postural hypotension, and syncope when used concomitantly with alfuzosin.

Source: NLP:alfuzosin hydrochloride

Concomitant use may increase risk of methemoglobinemia.

Source: NLP:dapsone

Data on concomitant use with captopril for heart failure are not available. Should be discontinued before starting captopril if possible; if resumed, administer cautiously at lower dosage.

Source: NLP:captopril

May increase certain actions or side effects of anticholinergic drugs including dicyclomine hydrochloride.

Source: NLP:dicyclomine hydrochloride

Vasodilators that antagonize pressor effects of epinephrine.

Source: NLP:epinephrine

Vasodilator that counters the pressor effects of epinephrine.

Source: NLP:epinephrine in sodium chloride

Used concomitantly with enalapril maleate without evidence of clinically significant adverse interactions.

Source: NLP:enalapril maleate

Enalapril has been used concomitantly without evidence of clinically significant adverse interactions.

Source: NLP:enalapril maleate and hydrochlorothiazide

Lisinopril has been used concomitantly with nitrates without evidence of clinically significant adverse interactions.

Source: NLP:lisinopril and hydrochlorothiazide

Nifedipine may be safely co-administered with long-acting nitrates, but no controlled studies evaluate antianginal effectiveness of combination.

Source: NLP:nifedipine