Antiperistaltic Antidiarrheal Drugs Interactions

May reduce absorption of hyoscyamine resulting in decreased therapeutic effectiveness. Doses should be spaced 1 hour apart.

Source: NLP:methenamine, sodium phosphate, monobasic, anhydrous, phenyl salicylate, methylene blue and hyoscyamine sulfate

Impair GI motility and decrease metoclopramide systemic absorption. Monitor for reduced therapeutic effect.

Source: NLP:metoclopramide

Potential for decreased metoclopramide effect due to opposing effects on gastrointestinal motility. Monitor for reduced effect.

Source: NLP:metoclopramide hydrochloride