Lomitapide Interactions

Coadministration is contraindicated. Itraconazole increases plasma concentrations, potentially increasing pharmacologic effects and adverse reactions.

Source: NLP:itraconazole

For patients with HoFH, do not exceed 10 mg/20 mg ezetimibe and simvastatin tablets daily; special restrictions apply for those chronically on higher simvastatin doses.

Source: NLP:ezetimibe and simvastatin

Approximately doubles simvastatin exposure and increases risk of myopathy and rhabdomyolysis.

Source: NLP:simvastatin