Tranquilizers Interactions

Concomitant use increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.

Source: NLP:buprenorphine hcl

Tranquilizers cause additive CNS depressant effects with carbinoxamine. Avoid concomitant use.

Source: NLP:carbinoxamine maleate

Additive CNS depression increasing risk of hypotension, respiratory depression, profound sedation, coma, and death.

Source: NLP:levorphanol tartrate

CNS depressant effect increases risk of respiratory depression, profound sedation, coma, and death.

Source: NLP:methadone hydrochloride

Concomitant use increases risk of respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.

Source: NLP:nalbuphine hydrochloride

Concomitant use increases risk of hypotension, respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.

Source: NLP:pentazocine and naloxone

Concomitant use may produce additive CNS depressant effects.

Source: NLP:pentobarbital sodium

Additive depressant effects with phenobarbital; toxic effects and fatalities have occurred with this combination.

Source: NLP:phenobarbital

Concomitant use of tranquilizers with barbiturates may produce additive central nervous system depressant effects.

Source: NLP:phenobarbital sodium

Promethazine may increase, prolong, or intensify the sedative action; avoid or use reduced dosage.

Source: NLP:promethazine hydrochloride

Promethazine may increase, prolong, or intensify sedative action of tranquilizers.

Source: NLP:promethazine hydrochloride and dextromethorphan hydrobromide

Antihistamine component has additive CNS depressant effects with tranquilizers.

Source: NLP:brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide

Antihistamines have additive effects with tranquilizers and other CNS depressants.

Source: NLP:brompheniramine maleate, pseudoephedrine hydrochloride,

Tranquilizers may have additive CNS depressant effects with cyproheptadine.

Source: NLP:cyproheptadine hydrochloride

Concomitant administration may result in further drowsiness due to CNS depressant effects.

Source: NLP:dantrolene sodium

Additive CNS depressant effects with diphenhydramine hydrochloride.

Source: NLP:diphenhydramine hydrochloride

Additive or potentiating CNS depressant effects; droperidol dose should be reduced when used concomitantly.

Source: NLP:droperidol

Additive sedative effects can occur when metoclopramide is given with tranquilizers.

Source: NLP:metoclopramide

Additive sedative effects can occur when metoclopramide is given with tranquilizers.

Source: NLP:metoclopramide hydrochloride

Promethazine may increase, prolong, or intensify sedative action; agents should be avoided or administered in reduced dosage.

Source: NLP:promethazine hydrochloride and phenylephrine hydrochloride

Known drug interaction with diphenoxylate hydrochloride; specific clinical effects not detailed in label.

Source: NLP:diphenoxylate hydrochloride and atropine sulfate