May enhance risk of hemorrhage. Discontinue prior to Lovenox initiation if possible, or conduct close clinical and laboratory monitoring if coadministration is essential.
Source: NLP:enoxaparin sodium
Sulfinpyrazone Interactions
13 interactions on record
Inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and toxicity risk while decreasing urinary levels and efficacy.
Source: NLP:nitrofurantoin
Inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and toxicity risk while decreasing urinary levels and efficacy as urinary tract antibacterial.
Source: NLP:nitrofurantoin monohydrate
Inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and toxicity risk while decreasing urinary levels and efficacy as urinary tract antibacterial.
Source: NLP:nitrofurantoin macrocrystals
CYP2C9 inhibitor that increases warfarin effect and INR; requires close INR monitoring
Source: NLP:warfarin
CYP2C9 inhibitor that increases warfarin effect and INR; requires closer INR monitoring.
Source: NLP:warfarin sodium
Salicylates antagonize the uricosuric action of sulfinpyrazone.
Source: NLP:aspirin and extended-release dipyridamole
Aspirin diminishes effectiveness of uricosuric agents in gout treatment by competing for protein binding sites.
Source: NLP:butalbital, aspirin, and caffeine
Sulfinpyrazone + GlimepirideModerate
May increase glucose-lowering effect of glimepiride, increasing susceptibility to and/or intensity of hypoglycemia.
Source: NLP:glimepiride
Sulfinpyrazone + NateglinideModerate
CYP2C9 inhibitor that may increase blood-glucose-lowering effect and susceptibility to hypoglycemia. Dose reductions and increased glucose monitoring may be required.
Source: NLP:nateglinide
Inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and potential toxicity while decreasing urinary levels and efficacy.
Source: NLP:nitrofurantoin (monohydrate/macrocrystals)
Salicylate inhibits the uricosuric effect of sulfinpyrazone.
Source: NLP:salicylic acid 10%
Sulfinpyrazone + SalsalateModerate
Salicylate competes with sulfinpyrazone for protein binding sites, potentially affecting drug levels.
Source: NLP:salsalate