Velpatasvir And Sofosbuvir + Sofosbuvir Interaction
Unknowninteraction on record
Description
John's wort, carbamazepine): May decrease concentrations of sofosbuvir and/or velpatasvir. ( 7.3 ) 7.1 Potential for Other Drugs to Affect EPCLUSA Sofosbuvir and velpatasvir are substrates of drug transporters P-gp and BCRP while GS-331007 (the predominant circulating metabolite of sofosbuvir) is not. John's wort, carbamazepine) may decrease plasma concentrations of sofosbuvir and/or velpatasvir, leading to reduced therapeutic effect of EPCLUSA.
Source: FDA drug label - velpatasvir and sofosbuvir