Trastuzumab + Cyclophosphamide Injection%2C Solution Interaction
Moderateinteraction on record
Description
• Thiazide diuretics • Zidovudine Increased cardiotoxicity • Anthracyclines • Cytarabine • Pentostatin • Radiation therapy of the cardiac region • Trastuzumab Increased pulmonary toxicity • Amiodarone • G-CSF, GM-CSF (granulocyte colony-stimulating factor, granulocyte macrophage colony-stimulating factor) Increased nephrotoxicity • Amphotericin B • Indomethacin: Acute water intoxication has been reported with concomitant use of indomethacin Increase in other toxicities: • Azathioprine: Increased risk of hepatotoxicity (liver necrosis) • Busulfan: Increased incidence of hepatic veno-occlusive disease and mucositis has been reported.
Source: FDA drug label - cyclophosphamide injection, solution