Tocilizumab + Simvastatin Interaction
Unknowninteraction on record
Description
In vivo studies with omeprazole, metabolized by CYP2C19 and CYP3A4, and simvastatin, metabolized by CYP3A4, showed up to a 28% and 57% decrease in exposure one week following a single dose of tocilizumab, respectively.
Source: FDA drug label - tocilizumab