Tenofovir + Emtricitabine%2C Rilpivirine Hydrochloride%2C And Tenofovir Alafenamide Interaction
Unknowninteraction on record
Description
7.6 Drugs Affecting Renal Function Because FTC and tenofovir are primarily excreted by the kidneys by a combination of glomerular filtration and active tubular secretion, coadministration of ODEFSEY with drugs that reduce renal function or compete for active tubular secretion may increase concentrations of FTC, tenofovir, and other renally eliminated drugs and this may increase the risk of adverse reactions. Narcotic Analgesics: methadone ↓ R(–) methadone ↓ S(+) methadone ↔ RPV ↔ methadone (when used with tenofovir) No dosage adjustments are required when initiating coadministration of methadone with ODEFSEY.
Source: FDA drug label - emtricitabine, rilpivirine hydrochloride, and tenofovir alafenamide