Temsirolimus Injection + Ketoconazole Interaction
Unknowninteraction on record
Description
7.2 Agents Inhibiting CYP3A Metabolism Co-administration of Temsirolimus injection with ketoconazole, a potent CYP3A4 inhibitor, had no significant effect on temsirolimus C max or AUC; however, sirolimus AUC increased 3.1-fold, and C max increased 2.2-fold compared to Temsirolimus injection alone.
Source: FDA drug label - temsirolimus injection