Telithromycin + Itraconazole Interaction

Majorinteraction on record

Description

Antibacterials telithromycin, in subjects with severe renal impairment or severe hepatic impairment rifabutin telithromycin Telithromycin: The potential increase in plasma concentrations of telithromycin in subjects with severe renal impairment or severe hepatic impairment, when coadministered with itraconazole may increase the risk of serious cardiovascular events including QT prolongation and torsade de pointes.

Source: FDA drug label - itraconazole