Sulfamethoxazole And Trimethoprim + Sulfamethoxazole Interaction
Unknowninteraction on record
Description
It has been reported that sulfamethoxazole and trimethoprim may prolong the prothrombin time in patients who are receiving the anticoagulant warfarin. This interaction should be kept in mind when sulfamethoxazole and trimethoprim is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed. Sulfamethoxazole and trimethoprim may inhibit the hepatic metabolism of phenytoin.
Source: FDA drug label - sulfamethoxazole and trimethoprim