Simvastatin + Eslicarbazepine Acetate Interaction
Unknowninteraction on record
Description
7.3 CYP3A4 Substrates In vivo studies suggest that eslicarbazepine acetate can induce CYP3A4, decreasing plasma concentrations of drugs that are metabolized by this isoenzyme (e.g., simvastatin, lovastatin) [see Clinical Pharmacology ( 12.3 )] . Dose adjustment of simvastatin and lovastatin may be needed if a clinically significant change in lipids is noted.
Source: FDA drug label - eslicarbazepine acetate