Simeprevir + Nexterone (Amiodarone Hci) Interaction

Majorinteraction on record

Description

7.3 Serious Symptomatic Bradycardia When Co-administered with Ledipasvir/Sofosbuvir or with Sofosbuvir with Simeprevir Postmarketing cases of symptomatic bradycardia, some requiring pacemaker insertion and at least one fatal, have been reported when ledipasvir/sofosbuvir or sofosbuvir with simeprevir were initiated in patients on amiodarone.

Source: FDA drug label - nexterone (amiodarone hci)