Rosuvastatin + Sofosbuvir%2C Velpatasvir%2C And Voxilaprevir Interaction
Moderateinteraction on record
Description
Coadministration of VOSEVI with BCRP substrates (e.g., methotrexate, mitoxantrone, imatinib, irinotecan, lapatinib, rosuvastatin, sulfasalazine, topotecan) is not recommended [see Clinical Pharmacology (12.3) ]. rosuvastatin ↑ rosuvastatin Coadministration of VOSEVI with rosuvastatin may significantly increase the concentration of rosuvastatin which is associated with increased risk of myopathy, including rhabdomyolysis. Coadministration of VOSEVI with rosuvastatin is not recommended.
Source: FDA drug label - sofosbuvir, velpatasvir, and voxilaprevir