Nifedipine + Promethazine%2C Phenylephrine%2C Codeine Interaction
Unknowninteraction on record
Description
7.10 Antihypertensive Drugs Due to the antagonistic pharmacologic effects of phenylephrine, one of the active ingredients in Promethazine and Phenylephrine HCl and Codeine Phosphate Oral Solution, the concomitant use of Promethazine and Phenylephrine HCl and Codeine Phosphate Oral Solution with antihypertensive drugs, including alpha-adrenergic antagonists (e.g., phentolamine); mixed alpha- and beta-adrenoreceptor antagonists; calcium channel blockers (e.g., nifedipine); ACE inhibitors; and centrally acting sympatholytic agents (e.g., guanfacine, reserpine) may reduce their antihypertensive effects.
Source: FDA drug label - promethazine, phenylephrine, codeine