Midazolam + Lansoprazole%2C Amoxicillin%2C Clarithromycin Interaction

Moderateinteraction on record

Description

Triazolobenzodiazepines and Other Related Benzodiazepines: Midazolam Use With Caution Midazolam : When oral midazolam is coadministered with clarithromycin, dose adjustments may be necessary and possible prolongation and intensity of effect should be anticipated (see WARNINGS ). In postmarketing experience, erythromycin has been reported to decrease the clearance of triazolam and midazolam, and thus, may increase the pharmacologic effect of these benzodiazepines.

Source: FDA drug label - lansoprazole, amoxicillin, clarithromycin